Summary of MAC Research

Since 2013, MAC investigators have advanced the understanding of Heritable Thoracic Aortic Disease (HTAD) through collaborative research, resulting in numerous publications in leading medical journals. Research generated through the consortium has expanded knowledge of the genetic causes, diagnosis, and management of these conditions, while informing international clinical guidelines and contributing to more personalized care for affected individuals and families.

To improve the diagnostic criteria of a growing list of conditions, now more than two dozen
To understand the natural and clinical histories of these conditions
To discover additional genetic variations that predispose individuals to Heritable Thoracic Aortic Disease (HTAD)
To discover and test new approaches to treatment
To facilitate collaborations in all of these endeavours
To translate research findings into clinical practice, educational resources, and evidence-informed care for individuals and families affected by HTAD

20+ Publications

Driving scientific discovery

280+ Citations

Influencing research globally

3 International Guidelines

Informing clinical practice