Why Join Mac
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- Why Join MAC
Joining the Montalcino Aortic Consortium (MAC) means becoming part of a global community of experts dedicated to advancing the understanding, diagnosis, and management of Heritable Thoracic Aortic Disease (HTAD). Through international collaboration, shared data, and multidisciplinary expertise, MAC is accelerating research discoveries, advancing clinical practice, and improving outcomes for patients and families around the world.
As a member, you will have the opportunity to contribute to impactful international research, collaborate with leaders in the field, and help drive the innovations that will define the next generation of aortic disease diagnosis, treatment, and care.
Richmond Jeremy, MBBS, PhD, FRACP
MAC Executive Committee Member
Professor in Medicine, Department of Cardiology
University of Sydney
Director, Marfan & Aortic Disease Clinic
Royal Prince Alfred Hospital
Drawing on his clinical experience, he explains how the Montalcino Aortic Consortium (MAC) helps clinicians better understand Heritable Thoracic Aortic Disease through collaborative research and shared data, enabling more personalized diagnosis, risk assessment, and treatment decisions. He highlights the importance of high-quality evidence in improving outcomes and helping patients, families, and healthcare providers make more informed decisions with confidence.
Collaborate With Global Leaders
MAC members work alongside internationally recognized experts in genetics, cardiology, cardiovascular surgery, and rare disease research. Through shared data, harmonized protocols, and collective expertise, members contribute to discoveries that cannot be achieved by single institutions alone.
Access High-Quality, Multinational Data
MAC maintains one of the world’s most comprehensive registries of Heritable Thoracic Aortic Diseases. Members have the opportunity to:
- Contribute patient data using standardized, high-quality protocols
- Participate in multi-site research initiatives
- Analyze large, rigorously curated datasets
- Support precision-medicine approaches that improve individualized care
Advance Research and Publish With Impact
MAC-driven studies lead to influential publications that shape clinical practice worldwide. Members have opportunities to:
- Propose and lead research projects
- Collaborate on major multicenter publications
- Contribute to guideline development and knowledge translation
- Strengthen academic profiles through high-impact authorship
Improve Patient Care and Clinical Excellence
MAC membership directly benefits clinical practice by providing:
- Evidence-informed insights for diagnosis and risk stratification
- Updated information on emerging genes and variant interpretation
- Clinical tools and best practices developed by international experts
- Improved pathways for family screening and patient follow-up
Membership enables clinicians to bring cutting-edge knowledge back to their institutions and communities.
Shape the Future of Precision Medicine
Through its global registry cores, working groups, and scientific summits, MAC drives the development of:
- New genotype–phenotype correlations
- Risk prediction models
- Improved surgical and medical management thresholds
- Research that supports targeted therapies and personalized care
Members play an active role in defining the next generation of aortic disease research.
Be Part of a Shared Mission
MAC was founded on the principles of collaboration, transparency, and a shared commitment to improving the lives of individuals and families affected by heritable aortic disease. Membership provides the opportunity to contribute to a global collaborative effort that is advancing research, accelerating discovery, improving patient care, and strengthening the international scientific community.