Why Join Mac

Join MAC and help advance research.
Apply now

Joining the Montalcino Aortic Consortium (MAC) means becoming part of a global network of leaders dedicated to advancing the science and clinical care of heritable thoracic aortic disorders. MAC unites clinicians, geneticists, surgeons, researchers, and data experts from internationally recognized institutions to accelerate discovery and improve outcomes for patients and families worldwide.

Membership in MAC offers a unique opportunity to collaborate across disciplines, contribute to large-scale international research, and shape the future of aortic disease diagnosis and treatment.

Collaborate With Global Leaders

MAC members work alongside internationally recognized experts in genetics, cardiology, cardiovascular surgery, and rare disease research. Through shared data, harmonized protocols, and collective expertise, members contribute to discoveries that cannot be achieved by single institutions alone.

Access High-Quality, Multinational Data

MAC maintains one of the world’s most comprehensive registries of heritable thoracic aortic diseases. Members have the opportunity to:

  • Contribute patient data using standardized, high-quality protocols
  • Participate in multi-site research initiatives
  • Analyze large, rigorously curated datasets
  • Support precision-medicine approaches that improve individualized care

Advance Research and Publish With Impact

MAC-driven studies lead to influential publications that shape clinical practice worldwide. Members have opportunities to:

  • Propose and lead research projects
  • Collaborate on major multicenter publications
  • Contribute to guideline development and knowledge translation
  • Strengthen academic profiles through high-impact authorship

Improve Patient Care and Clinical Excellence

MAC membership directly benefits clinical practice by providing:

  • Evidence-informed insights for diagnosis and risk stratification
  • Updated information on emerging genes and variant interpretation
  • Clinical tools and best practices developed by international experts
  • Improved pathways for family screening and patient follow-up

Membership enables clinicians to bring cutting-edge knowledge back to their institutions and communities.

Shape the Future of Precision Medicine

Through its global registry cores, working groups, and scientific summits, MAC drives the development of:

  • New genotype–phenotype correlations
  • Risk prediction models
  • Improved surgical and medical management thresholds
  • Research that supports targeted therapies and personalized care

Members play an active role in defining the next generation of aortic disease research.

Be Part of a Shared Mission

MAC was founded on collaboration, transparency, and a commitment to improving lives. Membership offers the chance to contribute to an international effort that is accelerating progress for families affected by aortic disease—and strengthening the scientific community as a whole.